Ruian Ke joined NC State in January 2015 as a Chancellor’s Faculty Excellence Program cluster hire in Personalized Medicine. He is an assistant professor in the Department of Mathematics and a member of the Comparative Medicine Institute. His research focuses on developing mathematical theories and tools to understand viral dynamics, treatments and immune responses across multiple scales of biological organization, including at intracellular, cellular and population scales. An overarching theme of his research is to elucidate emerging principles at higher scales arising from viral-host interactions at lower scales. He aims to use the theories and principles to address pertinent biological, clinical and epidemiological problems. Within the Personalized Medicine cluster, he has started projects involving development of mechanistic models to guide rational design of individualized treatment strategies.
Ruian Ke obtained a bachelor of science in mathematics from Heriot-Watt University in Edinburgh, U.K., where he received a Watt-Club Medal for achieving the greatest academic distinction. He then received a Ph.D. in mathematics and systems biology at Imperial College London and was honored with a Dorothy-Hodgkin Postgraduate Award. After obtaining his Ph.D., he decided to apply his mathematical skills to understand viral infection, evolution and treatment, with emphases on chronic infections such as HIV and hepatitis C virus. He then completed two post-doctoral trainings at University of California, Los Angeles, and Los Alamos National Laboratory.